{"id":9267,"date":"2017-03-03T22:48:36","date_gmt":"2017-03-03T19:48:36","guid":{"rendered":"https:\/\/hitmedia.su\/?p=9267"},"modified":"2019-03-12T14:56:57","modified_gmt":"2019-03-12T11:56:57","slug":"belok-teplovogo-shoka-vyzval-shok-informatsionnyj","status":"publish","type":"post","link":"https:\/\/hitmedia.su\/en\/2017\/03\/03\/belok-teplovogo-shoka-vyzval-shok-informatsionnyj\/","title":{"rendered":"”Heat shock protein” has caused information shock"},"content":{"rendered":"Reading time<\/span> 7<\/span> minutes<\/span><\/span>

[epapop id=’3958′]<\/p>\n

What happened?<\/h5>\n

On Friday, March 3, appeared in the media reports of a new universal remedy for cancer. It was introduced by the doctor of medical Sciences Andrey Simbirtsev told<\/a> about the invention of drugs, their properties and future production.<\/p>\n

A new drug called “heat shock proteins”, according to the Professor, is able to cure patients of all types of cancer.<\/p>\n

“We are on the verge of discovering completely new treatments for cancer. It will help people with incurable tumors.”<\/p><\/blockquote>\n

Institute of highly pure drugs of Federal medical-biological Agency (FMBA) have long been conducting research using space technology.<\/p>\n

\"Andrey
Andrey Simbirtsev, M. D., corresponding member of RAS, Deputy Director of the Institute of extra pure medications<\/figcaption><\/figure>\n

We Packed ultra-pure protein in capillary tubes and sent them to the ISS, says Simbirtsev. – The fact that for x-ray analysis of the action of the protein must be formed from it of ultra-pure crystal. However, in terms of earth’s gravity it is impossible to obtain.<\/p>\n

Scientists have obtained the required degree of purity of the drug, and after confirmed its harmless, should begin testing for clinical level.<\/p>\n

the Principle of operation of the new drug<\/h5>\n

The therapeutic effect is based on the introduction into the organism of a protein. This substance is synthesized by all cells under conditions of stress (e.g. heat shock) and performs a protective function, including secreting tumor antigens, enhancing the body’s immune response. However in the body this protein is not enough to defeat the disease. Therefore, scientists have developed a technology of its synthesis, and protein-based drug created the drug. It is argued that it operates on any cells, so it applies to treat all types of cancer.<\/p>\n

The drug is tested on small animals: mice and rats. In most cases, a medicine used to heal even the last stage of such common neoplastic diseases, such as sarcoma and melanoma. It was concluded that the drug “has the necessary biological activity for the treatment of cancer.”<\/p>\n

When the cure for cancer will be available?<\/h5>\n

The Institute has a grant for the first phase of research from the Ministry of education and science. Whether to continue development into clinical phase depends on funding.<\/p>\n

Clinical studies are very expensive, about 100 million rubles. Usually there is a private investor who invests, and the state returns 50% in case of successful completion, says Professor Simbirtsev. While the private investor is not found, there is hope to find it in Russia or in Japan, and the developer is counting on the support of the Ministry of health or Ministry of industry.<\/p>\n

According to the Professor, if the issue of funding is resolved, it will take another 3-4 years to complete the research before the drug gets to patients. On the expected cost of drugs are still unclear.<\/p>\n

Expert’s opinion<\/h5>\n

Ella Tyuryumina, research Intern of the HSE, engaged in research on “Predictive models in Oncology and their software support”:<\/p>\n

\"Ella“the Study doesn’t differ from the previous domestic. Pathetic presentation of the questionable results obtained on mice with artificially grown tumors. Unfortunately, such projects do not work in the clinic. With regard to the basic concept of the new method, it is “well forgotten old”. This approach has been known for a very long time ago.”<\/p><\/blockquote>\n

The expert has noticed that in the published data there is no reference to the registered randomized study (clinical trial, in which patients are allocated to treatment groups is random), and this “suggests that there was performed statistical analysis not given study design, were not selected patients on special teams.”<\/p>\n

\"Larissa
Larisa Fechina, oncologist, confidant of the President of the Russian Federation<\/figcaption><\/figure>\n

Larissa Fechina, oncologist interview<\/a> for NSN also questioned the creation of “some kind of universal magic pill”. The doctor is confident that the drug that can cure patients in the last stages of the disease, will be invented, but “the treatment is not addressed to all patients, and a certain group with a certain kind of cancer or multiple types of close nature. Victory over cancer will be possible in the era of personalized treatment,” said the doctor.<\/p>\n

Oleksiy Muravyov, lecturer of the HSE:<\/p>\n

\"Alex“While it is proved that the drug reacts with sarcoma and melanoma, but malignant tumors quite a lot, and they are not limited to these two. Therefore, all of these broadcast statements should be treated very carefully. And the technology well known, nothing new there”.<\/p><\/blockquote>\n

What’s in other countries?<\/h5>\n

The author of “heat shock protein” was told that a similar development is underway by scientists in the US and Japan, but so far their results have not been published.<\/p>\n

read More:<\/h4>\n